VIP: Phage Forward: Genomics & Therapeutic Applications
What is the overarching goal of this project?
Building on the foundational phage biology developed in BIOL 1111/1112 Bacteriophage Discovery & Genomics Labs (SEA-PHAGES), this course-based research experience (CURE) takes the next step: putting phages to work. Students will hunt for and characterize bacteriophages that infect pathogenic bacterial hosts, with a focus on uncovering genomic features and enzymes with real biotechnological and therapeutic potential.
What experience will students gain?
Working directly alongside graduate student mentors, participants contribute to active research projects investigating phage host range, jumbo phages, biofilm-degrading enzymes such as depolymerases, and phage candidates relevant to the treatment of bacterial infections. All experimental work is hypothesis-driven, and student findings feed directly into ongoing graduate-level research. Participants will have the opportunity to contribute to (and co-author) peer-reviewed publications.
VIP Faculty Lead information
Dr. Michael Thomas & Dr. Jack Shurley, along with grad students Sara Sadeghi, Aparajita Kabiraj, and Madison Nations.
Dr. Michael Thomas & Dr. Jack Shurley, along with grad students Sara Sadeghi, Aparajita Kabiraj, and Madison Nations.
"We're looking for students with a passion for phages!"
Registration Process:
By instructor permission. Priority given to students who have taken BIOL 1111/1112 Bacteriophage Discovery & Genomics Lab (SEA-PHAGES). Seats are limited. Students should reach out to one of the instructors or grad students before registration week to discuss career goals and research interests.