Jennifer Abbruzzese, M.S.
Introductory Biology Education
Office: Life Sciences 210
2000, M.S. Biology, Utah State University, Logan, UT
1996, B.A. Biology, Utah State University, Logan, UT
Ms. Abbruzzese has been an Assistant Lecturer in the Department of Biological Sciences at Idaho State University since 2012. Before coming to ISU, Ms. Abbruzzese worked as a Research Associate at the Nora Eccles Cardiovascular Research and Training Institute at the University of Utah. Ms. Abbruzzese received her Bachelor of Arts and Master of Science in Biology from Utah State University. Much of her training and research experience has involved the study of voltage-gated ion channels. Structure/function relationships, channelopathies, and drug development were a major focus of these studies.
Marzian, S., P. J. Stansfeld, M. Rapedius, S. Rinne, E. Nematian-Ardestani, J. L. Abbruzzese, K. Steinmeyer, M. S. Sansom, M. C. Sanguinetti, T. Baukrowitz, and N. Decher. 2013. Side pockets provide the basis for a new mechanism of Kv channel-specific inhibition. Nature Chemical Biology 9(8):507-13.
Grunnet, M., J. Abbruzzese, F.B. Sachse, and M.C. Sanguinetti. 2011. Molecular determinants of human ether-á-go-go-related gene 1 (hERG1) K+ channel activation by NS1643. Molecular Pharmacology 79 (1): 1-9.
Abbruzzese, J., F.B. Sachse, M. Tristani-Firouzi, and M.C. Sanguinetti. 2010. Modification of hERG1 channel gating by Cd2+. Journal of General Physiology 136 (2):203-224.
Perry, M., F.B. Sachse, J. Abbruzzese, and M.C. Sanguinetti. 2009. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance. Proceedings of the National Academy of Science 106 (47): 20075-20080.
Salvador-Retacala, V., W.J. Gallin, J. Abbruzzese, P.C. Ruben, and A.N. Spencer. 2006. A potassium channel (Kv4) cloned from the heart of the tunicate Ciona intestinalis and its modulation by a KChIP subunit. Journal of Experimental Biology 209 (4):731-747.
Dice, M., J. Abbruzzese, J. Wheeler, J. Groome, E. Fujimoto, and P.C Ruben. 2004. Temperature-sensitive defects in paramyotonia congenital mutants R1448C and T1313M. Muscle and Nerve 30:277-288.