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Gene Scalarone

Gene M. Scalarone, Ph.D.

Fungal Immunology

Office: Life Sciences 323

(208) 282-3374



1970, Ph.D. Immunology, University of California, Berkeley, CA
1965, M.S. Microbiology, University of Oklahoma, Norman, OK
1962, B.S. Biology, Pittsburg State University, Pittsburg, KS

Biographical Sketch

Dr. Scalarone has been a faculty member at ISU since 1980. His interest in medical mycology research began in 1962 as a microbiology graduate student at the University of Oklahoma. After completion of the MS degree in Microbiology, Dr. Scalarone served in the U.S. Army Medical Service Corps as Chief of Microbiology at Letterman General Hospital in San Francisco for two years. After obtaining his PhD degree in Immunology in 1970 from the University of California-Berkeley he continued there as a Research Bacteriologist (Naval BIOLciences Laboratory, School of Public Health, UC Berkeley) working on various aspects of fungal immunology. The research included work on the development and evaluation of antigenic reagents for the immunodiagnosis of coccidioidomycosis and histoplasmosis as well as research on fungal vaccines and antifungal agents. In addition to the research D. Scalarone became involved with teaching various microbiology courses at the UC Berkeley Extension Division, San Jose State University and Sonoma State University. Here at ISU he has continued research on the development of improved immunoassays for the clinical diagnosis of blastomycosis and other systemic fungal diseases. Research funding has been obtained from a variety of sources including two major NIH grants which allowed for the development and testing of novel yeast phase lysate antigenic reagents. His work in medical mycology also led to a sabbatical at the Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan. Many undergraduates and over 55 graduate students (MS and PhD) have completed degrees in Dr. Scalarone's laboratory at ISU since 1980. His research for over 50 years has resulted in over 275 presentations at regional, national and international scientific meetings as well as over 230 publications in various microbiology, immunology and medical mycology journals. Research continues on the development and evaluation of methods for the immunodiagnosis of blastomycosis and other fungal diseases of humans and animals.

Selected Publications

*Hammon, Jordan T., Austin C. Boyd & Gene M. Scalarone. 2015. Antibody detection in dogs with blastomycosis: Comparison of Blastomyces dermatitidis lysate antigens prepared from dog and soil isolates. US Open Veterinary Science & Veterinary Medicine Journal. Vol 1, No 2, pp. 1-7.

*Mondada, Katie, Jessie Fullmer, Eric Hungerford, Katrina Novack, Kristen Vickers & Gene Scalarone. 2014. Blastomyces dermatitidis: Antibody detection in sera from dogs with blastomycosis with yeast lysate antigens produced from human and dog isolates. Veterinary Medicine International (Hindawi Publishing Corporation, Vol. 2014 ID

*Hatch, Wayne O. & Gene M. Scalarone. 2013. Development of a slide agglutination assay for the detection of blastomycosis. Microbiology and Immunology (Wiley Publishing) 57:756-761.

*Searle, Amanda & Gene Scalarone. 2012. Comparative antibody study for antigen detection in urine specimens for diagnosis of blastomycosis using a competitive enzyme-linked immunosorbent assay. Open Journal of Immunology 2:139-143.

*Wright, Joshua C., Terrick E. Harrild & Gene M. Scalarone. 2012. Sensitivity and specificity determinations with isoelectric focusing fractions of Blastomyces dermatitidis for antibody detection in serum specimens from infected dogs. Open Journal of Veterinary Medicine 2:237-241.