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Idaho State University

Faculty

Professors   |   Lecturers   |   Postdoctoral Fellows    |   Emeritus   |   Affiliate

ISU Panorama. Photo by Chuck Peterson.

Professors

Vern Winston

Vern D. Winston, Ph.D.

Professor
Microbiology & Virology

Office: Life Sciences 425

(208) 282-2465

winsvern@isu.edu

Research Gate

Curriculum Vitae

Research


Lab: Life Sciences 422

Molecular virology. Computer modeling and simulation of protein function.

Teaching


BIOL 2235 - General Microbiology
BIOL 2206 - Cell Biology
BIOL 4475/5575 - General Virology
BIOL 4478/5578 - Animal Virology Laboratory
BIOL4491/4492 - Senior Seminar
BIOL 4494 - Microbiology Senior Seminar

BIOL 5579/6579 - Electron Microscopy
BIOL 6695 - Microbiology Graduate Seminar

Biographical Sketch


Dr. Winston joined the ISU faculty in 1980. In the ensuing 30+ years, he has been active in teaching in the Microbiology and Cell Biology curriculum (General Microbiology and Cell Biology) at the sophomore level, and his specialty (Virology) at the senior level. Dr. Winston's research has focused on a virus that is a major pathogen of fish in Idaho (Infectious Hematopoietic Necrosis Virus). Early on, this work was directed toward understanding the immune response of trout to the virus, and how the virus spreads from one fish to another. More recently the work has been directed toward studying the evolution of the virus, using molecular phylogeny and computer modeling techniques.

Education


Ph.D. Microbiology, University of Nebraska, Lincoln, NE
B.S. Microbiology, University of Nebraska, Lincoln, NE
Postdoctoral fellow, Structure of polyoma virus, Kansas State University, Manhattan, KS

Selected Publications


Bayless-Edwards L, Winston V, Lehmann-Horn F, Arinze P, Groome JR, Jurkat-Rott K. Na(V)1.4 DI-S4 periodic paralysis mutation R222W enhances inactivation and promotes leak current to attenuate action potentials and depolarize muscle fibers. Sci Rep. 2018 Jul 10;8(1):10372. doi: 10.1038/s41598-018-28594-5. PubMed PMID: 29991727; PubMed Central PMCID: PMC6039468.

Chung CH, Walter MH, Yang L, Chen SG, Winston V, Thomas MA. Predicting genome terminus sequences of Bacillus cereus-group bacteriophage using next generation sequencing data. BMC Genomics. 2017 May 4;18(1):350. doi: 10.1186/s12864-017-3744-0. PubMed PMID: 28472946; PubMed Central PMCID: PMC5418689.

Bednarz M, Stunnenberg BC, Kusters B, Kamsteeg EJ, Saris CG, Groome J, Winston V, Meola G, Jurkat-Rott K, Voermans NC. A novel Ile1455Thr variant in the skeletal muscle sodium channel alpha-subunit in a patient with a severe adult-onset proximal myopathy with electrical myotonia and a patient with mild paramyotonia phenotype. Neuromuscul Disord. 2017 Feb;27(2):175-182. doi: 10.1016/j.nmd.2016.09.023. Epub 2016 Oct 19. PubMed PMID: 28024841.

Groome JR, Lehmann-Horn F, Fan C, Wolf M, Winston V, Merlini L, Jurkat-Rott K. NaV1.4 mutations cause hypokalaemic periodic paralysis by disrupting IIIS4 movement during recovery. Brain. 2014 Apr;137(Pt 4):998-1008. doi:10.1093/brain/awu015. Epub 2014 Feb 18. PubMed PMID: 24549961; PubMed Central PMCID: PMC3959555.

Reed CJ, Lewis H, Trejo E, Winston V, Evilia C. Protein adaptations in archaeal extremophiles. Archaea. 2013;2013:373275. doi: 10.1155/2013/373275. Epub 2013 Sep 16. Review. PubMed PMID: 24151449; PubMed Central PMCID: PMC3787623.

Santin AE, Searle AJ, Winston VD, Powell MS, Hardy RW, Rodnick KJ. Glycated hemoglobin is not an accurate indicator of glycemia in rainbow trout. Comp Biochem Physiol A Mol Integr Physiol. 2013 Jul;165(3):343-52. doi:10.1016/j.cbpa.2013.04.012. Epub 2013 Apr 18. PubMed PMID: 23603514.