College of Pharmacy

ISU Home Page ISU GradCatalog 96/97 - Pharmacy

Pharmaceutical Sciences Graduate Courses

PSCI g423 Pharmaceutics I 3 credits. Fundamental knowledge for pharmaceutical evaluation: terminology, physical and chemical properties of drugs, and pharmacokinetic principles. Students become familiar with physician orders, patients' charts, current literature, and will evaluate patient profiles.

PSCI g424 Pharmaceutics II 4 credits. Pharmaceutical principles based on different routes of administration: biopharmaceutics, stability, packaging and formulation of various dosage forms; pharmacokinetic processes and dose modelling. Three hours lecture and three hours laboratory each week. PREREQ PSCI g423.

PSCI g425 Pharmaceutics III 4 credits. Parenterals, radiopharmaceuticals, chemotherapeutic products, biological derived products and manufacturing techniques. Three hours of lecture and three hours of laboratory each week. PREREQ: PSCI g424.

PSCI g455 Medicinal Chemistry I 3 credits. A study of the general chemistry, chemical properties and relationships between chemical structures and pharmacological activities of organic and inorganic medicinal agents. PREREQ: PSCI g465, BIOS g477.

PSCI g456 Medicinal Chemistry II 3 credits. A study of the general chemistry, chemical properties and relationships between chemical structures and pharmacological activities of organic and inorganic medicinal agents. PREREQ: PSCI g455.

PSCI g465 Pharmacology I 4 credits. Study of drug action, receptors and metabolism; principles of pharmacology of the major classes of drugs. PREREQ: BIOS 445, BIOS 449.

PSCI g466 Pharmacology II 4 credits. Study of drug action, receptors and metabolism; principles of pharmacology of the major classes of drugs. PREREQ: PSCI 465, BIOS 447, BIOS 456.

PSCI g467 Pharmacology III 3 credits. Principles of pharmacology of the major classes of drugs; the actions, receptor sites, and metabolism of these agents. PREREQ; PSCI g466, PSCI g455.

*PSCI g510 Pharmaceutical Analysis 3 credits. Principles and techniques of pharmaceutical analysis used for the evaluation of drugs and their dosage forms. PREREQ: PHAR 320, PCHM 308, BIOS 334, CHEM 206 OR PERMISSION OF INSTRUCTOR.

*PSCI g511 Vitamins and Enzymes 3 credits. Study of the biochemical role of vitamins and enzymes. PREREQ: BIOS 645, BIOS 477.

PSCI 515 Pharmacological Basis of Cancer Chemotherapy 3 credits. An in-depth study of the pharmacology of the antineoplastics and the rational basis for chemotherapy. Advances in the design and evaluation of newer combined treatments are included. Suitable for graduate credit. PREREQ: PSCI 465, PSCI 466.

PSCI 601 Graduate Seminar 1 credit. Discussion of current research and theories in Pharmaceutical Sciences. May be repeated.

PSCI 603 Scientific Wrting 2 credits. Basic techniques in scientific writing including: philosophy of science and logic in writing; how to write scientific papers, thesis/dissertation, grant proposals, and reviews; use of computers and software.

PSCI 605 Principles of Instrumental Techniques 3 credits. Discussion and practical experience in the use of instruments in Pharmaceutical Sciences research.

PSCI 606 Selected Techniques in the Laboratory 2 credits. Practical experience in the use of instrumentation and techniques in the student's area of specialization. Each student shall select three faculty laboratories in the Pharmaceutical Sciences for specific technical training. PREREQ: PERMISSION OF INSTRUCTOR.

PSCI 607 Research Foundations 2 credits. A discussion of the nature and critical analysis of experimentation, literature in the Pharmaceutical Sciences and styles of technical presentation. May be repeated.

PSCI 614 Structure Activity Relationships 3 credits. Examination of current theories of the relationship between chemical structure and biological activity. PREREQ: PCHM 611.

PSCI 622 Principles of Toxicology 3 credits. Introduction to basic concepts of toxicology, including mutagenesis, carcinogenesis, teratology, risk assessment, regulatory toxicology, toxicology of solvents, pesticides, metals and radioactive materials and design of toxicological studies. PREREQ: PSCI 621 OR PERMISSION OF INSTRUCTOR.

PSCI 651 Pharmacokinetic Theory 2 credits. A rigorous treatment of mathematical techniques involved in the derivation of equations describing the time-courses of drugs and metabolites in biological systems. PREREQ: GRADUATE STANDING AND PSCI 427, MATH 360.

PSCI 652 Pharmacokinetic Data Analysis 2 credits. A treatment of techniques involved in the analysis of pharmacokinetic data. PREREQ: GRADUATE STANDING AND PSCI 651.

PSCI 653 Biopharmaceutical Analysis 4 credits. A treatment of modern methods for the quantitative measurement of drugs and metabolites in biological materials. PREREQ: GRADUATE STANDING.

PSCI 654 Applied Pharmacokinetics 3 credits. Applications of pharmacokinetic concepts in the design of dosing regimens for specific drugs in individual subjects. PREREQ: PSCI 427.

PSCI 655 Biopharmaceutical Analysis II 2 credits. A continuation of 653, this course covers the nonchromatographic methods of analysis such as spectroscopy, immunoassays, radiochemical methods, fluorimetry, enzymatic assays, microbiological techniques, electroanalytical techniques, and electrophoresis.

PSCI 660 Mechanisms of Drug Action 3 credits. Advanced study in the transduction of biological signals, molecular basis for the action of hormones, neurotransmitters and growth factors on neurotransmission, metabolism, gene regulation and cell growth. PREREQ: PSCI 467 AND PERMISSION OF INSTRUCTOR.

PSCI 661 Drug Metabolism and Toxicology 3 credits. Advanced study in drug metabolism, cytochrome P450 oxidative system, toxic actions of drugs, mutagenicity, carcinogenicity, and in vitro systems for the study of toxicity, and risk assessment. PREREQ: PSCI 568 AND PERMISSION OF INSTRUCTOR.

PSCI 662 Advanced Neuropharmacology 3 credits. The molecular basis of drug action in the central nervous system including nerve excitation, molecular properties of ion channels, neuropharmacological methods, pharmacology of ethanol and the mechanisms in tolerance and physical dependence. PREREQ: PSCI 467 AND PERMISSION OF INSTRUCTOR.

PSCI 691 Topical Seminar in Pharmacology 2-4 credits. In-depth study of a current topic in pharmacology. May be repeated.

PSCI 698 Dissertation Research variable credit. A study of the current research literature dealing with the pharmacological action of drugs on cells, organs and organisms. PREREQ: PCOL 611.

PSCI 699 Dissertation variable credit. Preparation of the written report of the dissertation research. Graded S/U.

Pharmaceutics Graduate Courses

*PCEU g482 Independent Problems in Pharmacy 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.

PCEU 501 Drug Abuse and the Pharmacist 3 credits. A detailed discussion of pharmacological and societal aspects of drugs of abuse, including the role of the pharmacist when confronted with personal, professional, and societal drug abuse. PREREQ: PSCI 465.

PCEU 609 Advanced Pharmaceutics 3 credits. A study of the application of physiochemical principles to the design and formulation of pharmaceutical dosage forms. PREREQ: PHAR 312, PHAR 371 AND/OR PERMISSION OF INSTRUCTOR.

PCEU 610 Dispersed Systems 3 credits. The theoretical considerations of pharmaceutical dispersion systems including colloidal dispersions, interfacial phenomena, and electrokinetic and rheological properties. PREREQ: CHEM 352, PHAR 312 AND/OR PERMISSION OF INSTRUCTOR.

PCEU 611 Fundamentals of Percutaneous Absorption 3 credits. Structure and properties of skin and hair. Skin appendages, absorption models, nature of absorption, metabolism in the skin, protective action of skin, topical formulations. PREREQ: PCEU 610, PCEU 613 AND/OR PERMISSION OF INSTRUCTOR.

PCEU 613 Advanced Physical Pharmacy 3 credits. Physical-chemical principles involved in the formulation and evaluation of pharmaceuticalsystems, including degradation, stabilization, and complexation. PREREQ: CHEM 352, 571, PHAR607.

PCEU 615 Advanced Biopharmaceutics and Pharmacokinetics 3 credits. Physicochemical principles involved in the kinetics of drug absorption, distribution, biotransformation, elimination, and therapeutic response. PREREQ: PHAR 320, PCOL 352 AND/OR PERMISSION OF INSTRUCTOR.

PCEU 617 Advanced Biopharmaceutics and Pharmacokinetics II 3 credits. Application of the Physicochemical principles involved in the kinetics of drug absorption, distribution, biotransformation, elimination, and therapeutic response of drugs in studying and interpreting current research articles dealing with these parameters. PREREQ: PHAR615.

PCEU 649 Research in Pharmaceutics 1-2 credits per semester (may be repeated). Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.

PCEU 650 Thesis Research 1-10 credits.

*Electives

Pharmaceutical Chemistry Graduate Courses

PCHM g306 Inorganic Medicinal Chemistry 2 credits. A survey relating structures of inorganicmedicinal and pharmaceutical agents to their uses inpharmacy. PREREQ: CHEM 122 OR EQUIVALENT.

PCHM g307 Organic Medicinal Chemistry 3 credits. Systematic application of principles of structure activity relationships to the major classes of organic medicinal agents. PREREQ: CHEM 303, BIOS 232, AND BIOS 235.

PCHM g308 Organic Medicinal Chemistry 2 credits. Continuation of PCHM 307. PREREQ: PCHM 307.

*PCHM g412 Insecticides and Pesticides 3 credits. Study of the relationship between chemical structure and biological activity among the chemical agents used as insecticides and pesticides. PREREQ: CHEM 303 OR PERMISSION OF INSTRUCTOR.

*PCHM g482 Independent Problems in Pharmaceutical Chemistry 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.

PCHM 611 Advanced Medicinal Chemistry 3 credits. Advanced study of the chemical and biochemical nature of action of specific pharmacological agents. PREREQ: CHEM 521, CHEM 571, PHAR 607.

PCHM 621 Biological Actions of Chemicals 3 credits. Introduction to basic principles of pharmacology, including the molecular basis for drug action; entry, distribution, metabolism and elimination of chemicals in animal systems, genetic influences in chemical actions, and tolerance. PREREQ: PERMISSION OF INSTRUCTOR.

PCHM 649 Research in Pharmaceutical Chemistry 1-2 credits per semester (may be repeated). Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.

PCHM 650 Thesis Research 1-10 credits.

PCHM 691 Topical Seminar in Medicinal Chemistry 2-4 credits. In-depth study of a current topic in medicinal chemistry. May be repeated.

*Electives

Pharmacology Graduate Courses

PCOL g482 Independent Problems in Pharmacology 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.

PCOL 611 Advanced Pharmacology 3 credits. Pharmacological action of drugs on cells, organs, and organisms. PREREQ: PCOL 350, PCOL 351, PCOL 352, OR EQUIVALENT.

PCOL 615 Advanced Pharmacology II 3 credits. A study of the current research literature dealing with the pharmacological action of drugs on cells, organs and organisms. PREREQ: PCOL 611.

PCOL 632 Surgical and Experimental Methods in Pharmacology Research 2 credits. Advanced laboratory experience in surgical techniques used in pharmacology research. PREREQ: PCOL 352 AND/OR PERMISSION OF INSTRUCTOR.

PCOL 644 Drug Screening 3 credits. Study of the principles of detecting and evaluating new and/or novel drug activity. PREREQ: PCOL 352, PCHM AND/OR PERMISSION OF INSTRUCTOR.

PCOL 649 Research in Pharmacology 1-2 credits. Research problems ancillary to the thesisproject. May be repeated. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.

PCOL 650 Thesis Research 1-10 credits.

Pharmacy Administration Graduate Courses

PADM g454 Pharmacy Management I 2 credits. Principles of organization, management and financial analysis as applied to the practice of pharmacy. PREREQ: PPRA 519.

PADM g456 Pharmacy Management II 2 credits. Problems of management, merchandising, and salesmanship, applied to community pharmacy. PREREQ: PHAR 454.

PADM 538 Independent Problems in Pharmacy Administration 1-4 credits. Independent study of various topics in pharmacy administration. May be repeated.

PADM 601 Graduate Seminar in Pharmacy Administration 1 credit. Discussion of current research and theories in pharmacy administration. May be repeated.

PADM 603 Advanced Pharmacy Law 3 credits. Requirements of federal laws influencing the practice of pharmacy, including selected recent cases. PREREQ: PPRA 519 OR PERMISSION OF INSTRUCTOR.

PADM 605 Research Methods in Pharmacy Administration 3 credits. Methods in research design and analysis utilized in pharmacy administration research. PREREQ: MBA 602 OR EQUIVALENT GRADUATE LEVEL STATISTICS COURSE.

PADM 610 Social and Behavioral Aspects of Pharmacy Practice 3 credits. Examination of sociological and psychological concepts and theories as applied to the practice of pharmacy. PREREQ: PERMISSION OF INSTRUCTOR.

PADM 612 Ethics for Health Professionals 3 credits. Examination of ethical issues that arise in the provision of health care. PREREQ: PERMISSION OF INSTRUCTOR.

PADM 624 Advanced Pharmacy Management I 3 credits. Principles of operation and management encountered in the drug distribution process. PREREQ: ONE YEAR OF ACCOUNTING OR MBA 601, OR PERMISSION OF INSTRUCTOR.

PADM 626 Advanced Pharmacy Management II 3 credits. Case studies of problems encountered in pharmacy management. PREREQ: PADM 624.

PADM 630 Advanced Drug Marketing 3 credits. Approaches and methods of marketing as applied to pharmacy and the drug distribution process.

PADM 632 Medical Economics 3 credits. Examination of the market forces encountered in the medical care system.

PADM 634 Advanced Pharmacy Administration I 3 credits. An integration of socio-behavioral and management principles into an advanced consideration of pharmacy administration.

PADM 635 Advanced Pharmacy Administration II 3 credits. A continuation of PADM 634, this course further explores issues in the discipline of pharmacy administration.

PADM 649 Research in Pharmacy Administration 1-2 credits. Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.

PADM 650 Thesis Research 1-10 credits.

PADM 651 Master's Paper 3 credits.

PADM 691 Topical Seminar in Pharmacy Administration 2-4 credits. Examination of selected topics in pharmacy administration. May be repeated.

Pharmacy Practice Graduate Courses

PPRA g491 Topical Seminar in Pharmacy Practice 1-4 credits. Examination of selected topics in pharmacy practice and pharmacy administration. May be repeated. PREREQ: PERMISSION OF INSTRUCTOR.

PPRA g518 Clinical Research Design and Analysis 4 credits. The fundamentals of experimental design, implementation and data analysis pertinent to pharmaceutical clinical investigations.

PPRA 553 Professional Student Seminar 1 credit. Development of a relevant therapeutic topic including the review, analysis, and oral presentation of all appropriate medical and scientific literature. PREREQ: MUST BE FOURTH-YEAR PROFESSIONAL STUDENT.

PPRA 596 Clinical Pharmacy Residency 0 credits. Advance practical experience in clinical pharmacy practice. PREREQ: MUST HAVE A DOCTOR OF PHARMACY DEGREE.


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Revised: May 1, 1996

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