COLLEGE OF
PHARMACY

Arthur A. Nelson, Jr., Ph.D., Dean
Bernard W. Graham, Ph.D.,
Associate Dean

Department of
Pharmacy Practice and Administrative Sciences

Interim Chairman Graham
Professor and Dean Nelson
Professors Hurley, Maddox, Sharp
Associate Professors Adamcik, Culbertson, Gould, Mason, Rhodes Clinical Associate Professors Jue, Ratcliff Assistant Professors Bartlome', Cady, Erramouspe, Hefflinger, Matsuyama, Reitz
Clinical Assistant Professor Bokelmann, Cook

Department of
Pharmaceutical Sciences

Professor and Chairman Diedrich
Associate Professor and Associate Dean Graham Professors Dodson, Fontenelle, Garner, Goettsch, Isaacson Associate Professors Daniels, Jarvi, LaHann, Lai, Oberg, Torian Assistant Professors C. Nelson, Ratka, C. Senekowitsch, J. Senekowitsch Affiliate Professor Vestal
Affiliate Associate Professors Morgan, Olson, Stevens Affiliate Assistant Professors Charan, Cusack, Hadjokas, Nielson, Ramagopal

The College of Pharmacy offers two graduate degrees: the Master of Science (M.S.) in Pharmacy and the Doctor of Philosophy (Ph.D.) in Pharmaceutical Sciences. The College also offers a professional doctorate degree, Doctor of Pharmacy (Pharm.D.). The Pharm.D. is described in the College of Pharmacy section of the University Bulletin.

Master of Science in Pharmacy

The M.S. program offers the student a choice of five majors:

Major in Pharmaceutical Chemistry leading to the degree of M.S. in Pharmacy (Pharmaceutical Chemistry)
Major in Pharmacognosy leading to the degree of M.S. in Pharmacy (Pharmacognosy)
Major in Pharmacology leading to the degree of M.S. in Pharmacy (Pharmacology)
Major in Pharmaceutics leading to the degree of M.S. in Pharmacy (Pharmaceutics)
Major in Pharmacy Administration leading to the degree of M.S. in Pharmacy (Pharmacy Administration) Admission Requirements
To qualify for admission, a student must possess a professional degree in pharmacy (B.S. or Pharm.D.), or a baccalaureate degree in chemistry, biology, or a related field from an accredited institution, and have a grade point average of 3.0 or better over the last two years of undergraduate study. Students with a grade point average between 2.75 and 3.0 will receive consideration for admission on a conditional basis.
Other Requirements
Following the award of the professional degree, students would be changed to classified status.
All applicants are required to provide three letters of recommendation from professors from whom they have taken courses or under whose direction they have worked. It is highly recommended that the Graduate Record Examination be taken prior to the start of the semester in which a student begins graduate study. The GRE must be taken during the first semester in residence if it has not been taken previously.
All candidates are required to demonstrate a reading knowledge of a foreign language or proficiency with a research tool (such as computer programming and/or statistics). Individual requirements for each student must be approved by the student's major professor within the emphasis area.
All classified graduate students must register for the appropriate graduate seminar (601) each semester in which they are registered for graduate credit. A maximum of four credits in graduate seminar (601) may be applied toward the degree.
Early Entry Into the Graduate Program For Pharmacy Students Only
Professional students currently enrolled in the College of Pharmacy may be granted early admission to a graduate program administered by the College following completion of the second professional (P2) year in the Pharm.D. curriculum.
In order that a student be eligible for early admission to a graduate program in the College, the following criteria must be met:
1. Completion of at least 136 academic credits must be certified to the Graduate Dean by the Registrar. Such certification must include all University general education requirements; and all College of Pharmacy pre-pharmacy, first (P1) and second (P2) professional year course requirements in the Pharm.D. curriculum.
2. Minimum Graduate Record Examination scores: For admission to the M.S. program, attainment of scores on the GRE at the 35th percentile or better in either the verbal or quantitative portion of the test. For admission to the Ph.D. program, attainment of scores on the GRE at the 50th percentile.
3. Formal application for admission to the College graduate program, with acceptance as a conditional student by the appropriate department faculty. After meeting the above three criteria, a student may be admitted to the Graduate School on a conditional basis. Following the award of the Pharm.D. degree, the student may petition to change to classified status. Students should consult the Graduate School Bulletin for course requirements for the graduate degrees offered by the College.
  Master of Science in Pharmacy (Pharmaceutical Chemistry, Pharmaceutics, Pharmacognosy, or Pharmacology Emphasis)
  Candidates must complete the following courses:
```
PSCI 601            Graduate Seminar in the 
                    Pharmaceutical Sciences            2 cr
PSCI 607            Research Foundations in the
                    Pharmaceutical Sciences            2 cr
PSCI 650            Thesis Research                    6-10 cr
```
  Master of Science in Pharmacy (Pharmacy Administration Emphasis)
  Candidates may elect either a thesis or non-thesis option and must complete the following courses:
  M.S. DEGREE OPTION:
```
                                    NON-THESIS    THESIS
```
  STATISTICS AND
  RESEARCH METHODS
```
BIOS 605  Biometry                                4 cr
          OR
```
  PPRA 518 Clinical Research
```
          Design and Analysis           4 cr
PADM 605  Research Methods              3 cr      3 cr
```
  PHARMACY ADMINISTRATION
  MAJOR COURSES
  PADM 601 Graduate Seminar
```
          in Pharmacy Administration    2 cr      2 cr
```
  PADM 610 Social and Behavioral
```
          Aspects of Pharmacy Practice
          OR                            3 cr      3 cr
```
  PADM 632 Medical Economics
  PADM 634 Advanced Pharmacy
```
          Administration I              3 cr      3 cr
          OR   
```
  PADM 635 Advanced Pharmacy
```
          Administration II
          Major area elective courses   15 cr     12 cr
                                  Total 12 cr
```
  RESEARCH ACTIVITY
```
PADM 650  Thesis Research                         6 cr
PADM 651  Master's Paper                 3 cr
          Total                         33 cr    33 cr
```
  Maj/Min/Bach/Req/sub>Joint Pharm.D.-Graduate Degree Program (Pharmacy Administration Emphasis)
  Candidates must complete the following courses while enrolled in the P3 and P4 years of the Pharm.D. curriculum. (The courses listed below substitute for PSCI 532 Clinical Research Design and Analysis, and 6 credits of professional electives required in the Pharm.D. curriculum). In addition, the following courses taken in the P3 year will constitute a minor area in Clinical Pharmacy as required in the graduate program: PPRA 534 and PPRA 535 Therapeutics I and II, PSCI 529 Clinical Pharmacokinetics, and PSCI 568 Toxicology; PPRA 569 will substitute for 3 cr. of PADM 650 Thesis Research.
  Third Professional Year Course Substitutions:
```
BIOS 605            Biometry                           4 cr
                    OR
MBA 602             Survey of Business Statistical 
                    Techniques                         3 cr
PADM 605            Research Methods in Pharmacy
                    Administration                     3 cr
                    OR
MBA 630             Business Research                  3 cr
                    Pharmacy Administration            3 cr
                    Major Area Graduate Course
```
  Fourth Professional Year Elective Clerkship:
```
PPRA 569            Clinical Research Clerkship        4 cr
```
  Additional Graduate Program Requirements:
  M.S. (thesis option):
```
PADM 601            Graduate Seminar                   2 cr
                    Major Area Courses                12 cr
PADM 650            Thesis Research                    3 cr
                                                Total 17 cr
```
  Ph.D.:
```
PADM 601            Graduate Seminar                   4 cr
                    Multivariate Analysis              4 cr
                    Research Methods Elective          3 cr
                    Major Area Courses                21 cr
PSCI 698            Dissertation Research             18 cr
PSCI 699            Dissertation Prep                  1 cr
                                                Total 51 cr
```
  Doctor of Philosophy
  Programs of study leading to the Doctor of Philosophy (Ph.D.) degree are offered through the Department of Pharmaceutical Sciences (in the area of Pharmacology and in the general areas of Pharmacokinetics, Biopharmaceutics, and Biopharmaceutical Analysis) and through the Department of Pharmacy Practice and Administrative Sciences (in the area of Administration). Although a prescribed curriculum of course work is required, the Ph.D. degree is primarily a research degree to be conferred upon the completion and report of original work.
  Admission Requirements
  1. Professional degree in pharmacy or a baccalaureate degree in a related field with a GPA of not less than 3.0 for the final two years.
  2. Achieve at least the 50th percentile in two of the aptitude sections of the Graduate Record Examination (Verbal, Quantitative or Analytical).
  3. Three letters of recommendation. Applications for admission will be reviewed by the appropriate department (Pharmaceutical Sciences or Pharmacy Practice and Administrative Sciences) and forwarded to the Graduate Education and Faculty Research Affairs Committee for recommendation to the chairperson of the department in which the student will pursue the degree. Applications approved by the department chairperson will be transmitted to the Dean of the College, who will in turn send them to the Dean of Graduate Studies for final approval. A preliminary examination (within two weeks of registration) may be necessary for students who wish to demonstrate proficiencies which are required for admission but not clearly documented in the application materials. Such deficiencies should be removed during the first two semesters of residence.
    Program of Study and Degree Requirements
    Each beginning student will have a graduate advisor assigned from the graduate faculty upon entry into the program. The graduate advisor will assist the student in selecting an appropriate program of course work for the first year. With the assistance of the graduate advisor, the student will be expected to select a major advisor from the graduate faculty no later than the end of the third semester in residence. The chairperson will be notified of this selection in writing by the student and the major advisor prior to the end of the semester. During the semester following the selection of the major advisor, an advisory committee will be appointed. This committee, chaired by the major advisor, will consist of four graduate faculty members, one of whom is from outside the student's department. The committee must be approved by the department chairperson and the Graduate Education and Faculty Research Affairs Committee prior to the end of the semester.
    Within one semester of the committee's appointment, the student's degree plan will be formulated. The overall plan will include at least 72 semester hours of graduate course work, not less than 18 semester hours of which must include PSCI 698 (Dissertation Research) and PSCI 699 (Dissertation), and will be completed after admission to candidacy. The degree plan must also include six semester hours of PSCI 601 (Graduate Seminar in Pharmaceutical Sciences), one hour of which will require the preparation and defense of a grant proposal.
    A grade below B is unsatisfactory and will not be counted toward fulfilling the minimum requirements for the degree. Upon recommendation of the student's advisory committee and with the approval of the department chairperson, a student may be required to withdraw at any time for failure to maintain satisfactory progress toward the degree.
    Comprehensive Examination
    After completion of not less than 48 semester hours and upon the recommendation of the advisory committee, the student may be examined for admission to candidacy. A written comprehensive examination will be administered by each committee member. Upon satisfactory completion of each written examination, an oral comprehensive examination will be administered during a meeting of the committee. The oral examination may include the proposal and defense of the student's dissertation research plan, supported by sufficient preliminary data.
    All comprehensive examinations for an individual student will be completed within a two-week period. Admission to candidacy requires a majority vote of the advisory committee. A student failing to receive a majority vote may petition to the advisory committee and the department chairman to take a second examination, no sooner than three months after the first comprehensive examination. Successful completion of the second examination requires the vote of all committee members. Failure on the second examination will render the student ineligible to continue in the Ph.D. program.
    Admission to Candidacy
    Upon written notification that the student has successfully passed all comprehensive examinations, the chairperson will recommend to the Dean of Graduate Studies that the student be admitted to candidacy and the Graduate Faculty Representative appointed.
    Dissertation
    Upon completion of all proposed research, the student's findings will be reported in the form of a dissertation to be prepared in accordance with department and graduate school guidelines. While the dissertation must be defended to the graduate faculty of the College, acceptability only requires the affirmative vote of a majority of the student's committee members.
    Doctor of Philosophy in Pharmaceutical Sciences (Pharmacy Administration Emphasis)
    Candidates must complete the following courses:
    Statistics and Research Methods (14 credits)
```
BIOS 605            Biometry                           4 cr
                    Multivariate Analysis              4 cr
PADM 605            Research Methods                   3 cr
                    One additional methods course 
                    (e.g.3 cr MBA 630, SOC 508, 
                    PSYC 632)                          3 cr
```
    Pharmacy Administration Major Courses (28 credits)
```
PADM 601            Graduate Seminar in Pharmacy 
                    Administration                     4 cr
PADM 610            Social and Behavior Aspects of 
                    Pharmacy Practice                  3 cr
PADM 632            Medical Economics                  3 cr
PADM 634            Advanced Pharmacy 
                    Administration I                   3 cr
PADM 635            Advanced Pharmacy 
                    Administration II                  3 cr
                    Major area elective courses       12 cr
```
    Minor Area Courses (12 credits)*
```
                    Minor area elective courses       12 cr
```
    Research Activities (19 credits minimum)**
```
PADM 650            Thesis Research**                  3 cr
PSCI 698            Dissertation Research             18 cr
PSCI 699            Dissertation Preparation           1 cr
                                             Total 73-76 cr
```
    *A student entering the Ph.D. program with a M.S. degree in a related area may petition the Advisory Committee to waive the elective 12 credits required in a minor area of study.
    **All students must have research experience prior to beginning the dissertation. If a student has not completed a M.S. thesis, then s/he must complete a minimum of 3 credits of graduate research (PADM 650) and complete a research project resulting in a paper of publishable quality. If a student has completed a M.S. thesis, s/he may petition the Advisory Committee to accept it as fulfillment of this requirement.
    Pharmaceutical Sciences
    Graduate Courses
    PSCI g465 Pharmacology I 4 credits. Study of drug action, receptors and metabolism; principles of pharmacology of the major classes of drugs. PREREQ: BIOS 445, BIOS 449.
    PSCI g466 Pharmacology II 4 credits. Study of drug action, receptors and metabolism; principles of pharmacology of the major classes of drugs. PREREQ: PSCI 465, BIOS 447, BIOS 456.
    PSCI g467 Pharmacology III 4 credits. Study of drug action, receptors and metabolism; principles of pharmacology of the major classes of drugs. PREREQ: PSCI 466, PSCI 455, BIOS 463.
    *PSCI g510 Pharmaceutical Analysis 3 credits. Principles and techniques of pharmaceutical analysis used for the evaluation of drugs and their dosage forms. PREREQ: PHAR 320, PCHM 308, BIOS 334, CHEM 206 OR PERMISSION OF INSTRUCTOR.
    *PSCI g511 Vitamins and Enzymes 3 credits. Study of the biochemical role of vitamins and enzymes. PREREQ: CHEM 332.
    PSCI 515 Pharmacological Basis of Cancer Chemotherapy 3 credits. An in-depth study of the pharmacology of the antineoplastics and the rational basis for chemotherapy. Advances in the design and evaluation of newer combined treatments are included. Suitable for graduate credit. PREREQ: PSCI 465, PSCI 466.
    *PSCI g520 Manufacturing Pharmacy 2 credits. Study of manufacturing processes, control procedures, and equipment used in the manufacture of pharmaceutical products on a small plant scale. PREREQ: PSCI 326, PSCI 327.
    PSCI 601 Graduate Seminar in the Pharmaceutical Sciences 1 credit. Discussion of current research and theories in the several pharmaceutical sciences. May be repeated.
    PSCI 607 Research Foundations in the Pharmaceutical Sciences 2 credits. A discussion of the nature of experimentation, literature in pharmaceutical science and styles of technical presentation.
    PSCI 614 Structure Activity Relationships 3 credits. Examination of current theories of the relationship between chemical structure and biological activity. PREREQ: PCHM 611.
    PSCI 622 Principles of Toxicology 3 credits. Introduction to basic concepts of toxicology, including mutagenesis, carcinogenesis, teratology, risk assessment, regulatory toxicology, toxicology of solvents, pesticides, metals and radioactive materials and design of toxicological studies. PREREQ: PSCI 621.
    PSCI 650 Thesis Research 1-10 credits.
    PSCI 651 Pharmacokinetic Theory 2 credits. A rigorous treatment of mathematical techniques involved in the derivation of equations describing the time-courses of drugs and metabolites in biological systems. PREREQ: GRADUATE STANDING AND PSCI 427, MATH 360.
    PSCI 652 Pharmacokinetic Data Analysis 2 credits. A treatment of techniques involved in the analysis of pharmacokinetic data. PREREQ: GRADUATE STANDING AND PSCI 651.
    PSCI 653 Biopharmaceutical Analysis 4 credits. A treatment of modern methods for the quantitative measurement of drugs and metabolites in biological materials. PREREQ: GRADUATE STANDING.
    PSCI 654 Applied Pharmacokinetics 3 credits. Applications of pharmacokinetic concepts in the design of dosing regimens for specific drugs in individual subjects. PREREQ: PSCI 427.
    PSCI 655 Biopharmaceutical Analysis II 2 credits. A continuation of 653, this course covers the nonchromatographic methods of analysis such as spectroscopy, immunoassays, radiochemical methods, fluorimetry, enzymatic assays, microbiological techniques, electroanalytical techniques, and electrophoresis.
    PSCI 660 Mechanisms of Drug Action 3 credits. Advanced study in the transduction of biological signals, molecular basis for the action of hormones, neurotransmitters and growth factors on neurotransmission, metabolism, gene regulation and cell growth. PREREQ: PSCI 467 AND PERMISSION OF INSTRUCTOR.
    PSCI 661 Drug Metabolism and Toxicology 3 credits. Advanced study in drug metabolism, cytochrome P450 oxidative system, toxic actions of drugs, mutagenicity, carcinogenicity, and in vitro systems for the study of toxicity, and risk assessment. PREREQ: PSCI 568 AND PERMISSION OF INSTRUCTOR.
    PSCI 662 Advanced Neuropharmacology 3 credits. The molecular basis of drug action in the central nervous system including nerve excitation, molecular properties of ion channels, neuropharmacological methods, pharmacology of ethanol and the mechanisms in tolerance and physical dependence. PREREQ: PSCI 467 AND PERMISSION OF INSTRUCTOR.
    PSCI 691 Topical Seminar in Pharmacology 2-4 credits. In-depth study of a current topic in pharmacology. May be repeated.
    PSCI 698 Dissertation Research variable credit. A study of the current research literature dealing with the pharmacological action of drugs on cells, organs and organisms. PREREQ: PCOL 611.
    PSCI 699 Dissertation variable credits. Preparation of the written report of the dissertation research. Graded S/U.
    Pharmaceutics
    Graduate Courses
    *PCEU g482 Independent Problems in Pharmacy 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.
    PCEU 501 Drug Abuse and the Pharmacist 3 credits. A detailed discussion of pharmacological and societal aspects of drugs of abuse, including the role of the pharmacist when confronted with personal, professional, and societal drug abuse. PREREQ: PSCI 465.
    PCEU 609 Advanced Pharmaceutics 3 credits. A study of the application of physiochemical principles to the design and formulation of pharmaceutical dosage forms. PREREQ: PHAR 312, PHAR 371 AND/OR PERMISSION OF INSTRUCTOR.
    PCEU 610 Dispersed Systems 3 credits. The theoretical considerations of pharmaceutical dispersion systems including colloidal dispersions, interfacial phenomena, and electrokinetic and rheological properties. PREREQ: CHEM 352, PHAR 312 AND/OR PERMISSION OF INSTRUCTOR.
    PCEU 611 Fundamentals of Percutaneous Absorption 3 credits. Structure and properties of skin and hair. Skin appendages, absorption models, nature of absorption, metabolism in the skin, protective action of skin, topical formulations. PREREQ: PCEU 610, PCEU 613 AND/OR PERMISSION OF INSTRUCTOR.
    PCEU 613 Advanced Physical Pharmacy 3 credits. Physical-chemical principles involved in the formulation and evaluation of pharmaceutical systems, including degradation, stabilization, and complexation. PREREQ: CHEM 352, 571, PHAR 607.
    PCEU 615 Advanced Biopharmaceutics and Pharmacokinetics 3 credits. Physicochemical principles involved in the kinetics of drug absorption, distribution, biotransformation, elimination, and therapeutic response. PREREQ: PHAR 320, PCOL 352 AND/OR PERMISSION OF INSTRUCTOR.
    PCEU 617 Advanced Biopharmaceutics and Pharmacokinetics II 3 credits. Application of the Physicochemical principles involved in the kinetics of drug absorption, distribution, biotransformation, elimination, and therapeutic response of drugs in studying and interpreting current research articles dealing with these parameters. PREREQ: PHAR 615.
    PCEU 649 Research in Pharmaceutics 1-2 credits per semester (may be repeated). Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.
    PCEU 650 Thesis Research 1-10 credits.
    *Electives
    Pharmaceutical Chemistry
    Graduate Courses
    PCHM g306 Inorganic Medicinal Chemistry 2 credits. A survey relating structures of inorganic medicinal and pharmaceutical agents to their uses in pharmacy. PREREQ: CHEM 122 OR EQUIVALENT.
    PCHM g307 Organic Medicinal Chemistry 3 credits. Systematic application of principles of structure activity relationships to the major classes of organic medicinal agents. PREREQ: CHEM 303, BIOS 232, AND BIOS 235.
    PCHM g308 Organic Medicinal Chemistry 2 credits. Continuation of PCHM 307. PREREQ: PCHM 307.
    *PCHM g412 Insecticides and Pesticides 3 credits. Study of the relationship between chemical structure and biological activity among the chemical agents used as insecticides and pesticides. PREREQ: CHEM 303 OR PERMISSION OF INSTRUCTOR.
    *PCHM g482 Independent Problems in Pharmaceutical Chemistry 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.
    PCHM 611 Advanced Medicinal Chemistry 3 credits. Advanced study of the chemical and biochemical nature of action of specific pharmacological agents. PREREQ: CHEM 521, CHEM 571, PHAR 607.
    PCHM 620 Chemistry of Natural Products 3 credits. Advanced study of the chemistry and biosynthesis of naturally occurring compounds of medicinal interest. Cross-listed with Pharmacognosy.PREREQ: PCHM 611 AND/OR PCOG 611 OR PERMISSION OF INSTRUCTOR.
    PCHM 621 Biological Actions of Chemicals 3 credits. Introduction to basic principles of pharmacology, including the molecular basis for drug action; entry, distribution, metabolism and elimination of chemicals in animal systems, genetic influences in chemical actions, and tolerance. PREREQ: PERMISSION OF INSTRUCTOR.
    PCHM 649 Research in Pharmaceutical Chemistry 1-2 credits per semester (may be repeated). Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.
    PCHM 650 Thesis Research 1-10 credits.
    PCHM 691 Topical Seminar in Medicinal Chemistry 2-4 credits. In-depth study of a current topic in medicinal chemistry. May be repeated.
    *Electives
    Pharmacognosy
    Graduate Courses
    PCOG g304 Pharmacognosy 3 credits. Study of selected plant, animal, and microbial products used as drugs; their biosynthesis, isolations, and therapeutic utilization. PREREQ: PHAR 311, BIOS 332, BIOS 334.
    PCOG g305 Pharmacognosy 4 credits. Continuation of PCOG 304. PREREQ: PCOG 304, BIOS 235.
    *PCOG g411 Microanalytical Procedures 3 credits. Study of microanalytical methods utilized in the examination of foods and drugs of natural origin. Emphasis on optical microscopic and microchemical techniques. PREREQ: PCOG 305 OR PERMISSION OF INSTRUCTOR.
    *PCOG g413 Poisonous Plants 3 credits. Plants responsible for poisoning in man and domestic animals, with emphasis on the chemistry and toxicology of the offending constituents. PREREQ: PCOG 305 OR PERMISSION OF INSTRUCTOR.
    *PCOG g482 Independent Problems in Pharmacognosy 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.
    PCOG 691 Topical Seminar in Pharmacognosy 2-4 credits. In-depth study of a current topic in pharmacognosy. May be repeated.
    *Electives
    Pharmacology
    Graduate Courses
    PCOL g350 Pharmacodynamics I 4 credits. Beginning study of drug absorption, metabolism and excretion and the effects of these parameters on age and nutrition. Selected drugs which influence metabolic and endocrine function will be included in detail. PREREQ: PERMISSION OF INSTRUCTOR.
    PCOL g351 Pharmacodynamics II 4 credits. Presentation of the principles of pharmacology of the major classes of drugs. PREREQ: PERMISSION OF INSTRUCTOR.
    PCOL g352 Pharmacodynamics III 4 credits. Continuation of PCOL 351. PREREQ: PCOL 351.
    PCOL g410 Chemotherapy 4 credits. Lectures concerning the genesis and therapy of cancer and microbial disorders. PREREQ: PCOL 352, BIOS 332 OR PERMISSION OF INSTRUCTOR.
    PCOL g412 Toxicology 3 credits. Study of the symptomology, cause, and treatment of acute and chronic poisoning. PREREQ: PCOL 350, PCOL 351, PCOL 352, OR PERMISSION OF INSTRUCTOR.
    PCOL g482 Independent Problems in Pharmacology 1-2 credits. Advanced students are assigned special laboratory studies on the basis of interest and previous preparation. PREREQ: PERMISSION OF INSTRUCTOR.
    PCOL 611 Advanced Pharmacology 3 credits. Pharmacological action of drugs on cells, organs, and organisms. PREREQ: PCOL 350, PCOL 351, PCOL 352, OR EQUIVALENT.
    PCOL 615 Advanced Pharmacology II 3 credits. A study of the current research literature dealing with the pharmacological action of drugs on cells, organs and organisms. PREREQ: PCOL 611.
    PCOL 632 Surgical and Experimental Methods in Pharmacology Research 2 credits. Advanced laboratory experience in surgical techniques used in pharmacology research. PREREQ: PCOL 352 AND/OR PERMISSION OF INSTRUCTOR.
    PCOL 644 Drug Screening 3 credits. Study of the principles of detecting and evaluating new and/or novel drug activity. PREREQ: PCHM 308 , PCOL 352 AND/OR PERMISSION OF INSTRUCTOR.
    PCOL 649 Research in Pharmacology 1-2 credits. Research problems ancillary to the thesis project. May be repeated. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.
    PCOL 650 Thesis Research 1-10 credits.
    Pharmacy Administration
    Graduate Courses
    PADM g454 Pharmacy Management I 2 credits. Principles of organization, management and financial analysis as applied to the practice of pharmacy. PREREQ: PPRA 519.
    PADM g456 Pharmacy Management II 2 credits. Problems of management, merchandising, and salesmanship, applied to community pharmacy. PREREQ: PHAR 454.
    PADM 538 Independent Problems in Pharmacy Administration 1-4 credits. Independent study of various topics in pharmacy administration. May be repeated.
    PADM 601 Graduate Seminar in Pharmacy Administration 1 credit. Discussion of current research and theories in pharmacy administration. May be repeated.
    PADM 603 Advanced Pharmacy Law 3 credits. Requirements of federal laws influencing the practice of pharmacy, including selected recent cases. PREREQ: PPRA 519 OR PERMISSION OF INSTRUCTOR.
    PADM 605 Research Methods in Pharmacy Administration 3 credits. Methods in research design and analysis utilized in pharmacy administration research. PREREQ: MBA 602 OR EQUIVALENT GRADUATE LEVEL STATISTICS COURSE.
    PADM 610 Social and Behavioral Aspects of Pharmacy Practice 3 credits. Examination of sociological and psychological concepts and theories as applied to the practice of pharmacy. PREREQ: PERMISSION OF INSTRUCTOR.
    PADM 612 Ethics for Health Professionals 3 credits. Examination of ethical issues that arise in the provision of health care. PREREQ: PERMISSION OF INSTRUCTOR.
    PADM 624 Advanced Pharmacy Management I 3 credits. Principles of operation and management encountered in the drug distribution process. PREREQ: ONE YEAR OF ACCOUNTING OR MBA 601, OR PERMISSION OF INSTRUCTOR.
    PADM 626 Advanced Pharmacy Management II 3 credits. Case studies of problems encountered in pharmacy management. PREREQ: PADM 624.
    PADM 630 Advanced Drug Marketing 3 credits. Approaches and methods of marketing as applied to pharmacy and the drug distribution process.
    PADM 632 Medical Economics 3 credits. Examination of the market forces encountered in the medical care system.
    PADM 634 Advanced Pharmacy Administration I 3 credits. An integration of socio-behavioral and management principles into an advanced consideration of pharmacy administration.
    PADM 635 Advanced Pharmacy Administration II 3 credits. A continuation of PADM 634, this course further explores issues in the discipline of pharmacy administration.
    PADM 649 Research in Pharmacy Administration 1-2 credits. Research problems ancillary to the thesis project. PREREQ: GRADUATE STANDING AND PERMISSION OF INSTRUCTOR.
    PADM 650 Thesis Research 1-10 credits.
    PADM 651 Master's Paper 3 credits.
    PADM 691 Topical Seminar in Pharmacy Administration 2-4 credits. Examination of selected topics in pharmacy administration. May be repeated.
    Pharmacy Practice
    Graduate Courses
    PPRA g491 Topical Seminar in Pharmacy Practice 1-4 credits. Examination of selected topics in pharmacy practice and pharmacy administration. May be repeated. PREREQ: PERMISSION OF INSTRUCTOR.
    PPRA g518 Clinical Research Design and Analysis 4 credits. The fundamentals of experimental design, implementation and data analysis pertinent to pharmaceutical clinical investigations.